SCHEMBL20090416

SCHEMBL20090416

COc1ccc(C[PH](=O)c2ccccc2-c2ccccc2O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
NSD2 O96028 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
RAB9A P51151 4/20 0.41
NPC1 O15118 4/20 0.41
TDP1 Q9NUW8 1/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
MAPT P10636 2/20 0.40
GAA P10253 1/20 0.40
PKM P14618 1/20 0.40
PTGDR Q13258 1/20 0.40
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22732401 0.74 ALDH1A1 (0.38) TDP1LMNAALOX15MAPT
SCHEMBL971238 0.72 LTA4H (0.53) MEN1KMT2ANSD2L3MBTL1RAB9A
SCHEMBL23114236 0.71 TSHR (0.41) MEN1KMT2AL3MBTL1RAB9ANPC1
SCHEMBL8385753 0.68 CMA1 (0.50) ALOX15ALOX12LTA4H
SCHEMBL31612942 0.68 LMNA (0.56) MEN1KMT2ARAB9ANPC1KDM4E
SCHEMBL4753994 0.68 NPC1 (0.63) MEN1KMT2ARAB9ANPC1KDM4E
SCHEMBL12284074 0.68 HPGD (0.41) MEN1KMT2AL3MBTL1RAB9ANPC1
Formaldehyde SCHEMBL27994586 0.67 HPGD (0.56) MEN1KMT2ARAB9ANPC1KDM4E
SCHEMBL258524 0.67 ALDH1A1 (0.47) L3MBTL1TDP1LMNAALOX15MAPT
SCHEMBL9068308 0.67 NPC1 (0.53) MEN1KMT2ARAB9ANPC1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180112133-A1 SILOXANE-MODIFIED CYCLOTRIPHOSPHAZENE HALOGEN-FREE FLAME RETARDANT, PREPARATION PROCESS AND USE THEREOF SHENGYI TECHNOLOGY CO., LTD. (CN) 2018-04-26 US disclosed