Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 8/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25643969 | 0.96 | MEN1 (0.52) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20156851 | 0.91 | MEN1 (0.53) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20156933 | 0.91 | MEN1 (0.53) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20156908 | 0.86 | NPC1 (0.54) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22373677 | 0.85 | RAB9A (0.53) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL25162663 | 0.84 | RAB9A (0.49) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22308562 | 0.83 | MEN1 (0.56) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16376445 | 0.83 | MEN1 (0.58) | KMT2AMEN1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL16376452 | 0.83 | MEN1 (0.58) | KMT2AMEN1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL16201494 | 0.83 | MEN1 (0.58) | KMT2AMEN1RAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730812-B2 | Double spiro compound and organic light-emitting element comprising same | LG CHEM, LTD. (KR) | 2020-08-04 | — | — | US | disclosed |
| US-20180111887-A1 | DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730812-B2 | Double spiro compound and organic light-emitting element comprising same | NR2E3, CRY1, CRY2 | KMT2A 896/4885MEN1 696/4885RAB9A 2549/4885 |
| US-20180111887-A1 | DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | NR2E3, CRY1, CRY2 | KMT2A 896/4885MEN1 696/4885RAB9A 2549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.