SCHEMBL2009154

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2003926	0.84	CNR1 (0.40)	NPSR1CNR1ALDH1A1MAPTTSHR
	SCHEMBL3060089	0.82	CNR1 (0.46)	CNR1ALDH1A1TSHRKMT2AMEN1
	SCHEMBL2005265	0.82	SMN1; SMN2 (0.48)	CNR1ALDH1A1TSHRKMT2AMEN1
	SCHEMBL2010721	0.82	PKM (0.51)	CNR1ALDH1A1TSHRKMT2AMEN1
	SCHEMBL2007289	0.82	MEN1 (0.47)	NPSR1CNR1ALDH1A1MAPTTSHR
	SCHEMBL2006592	0.82	MEN1 (0.47)	NPSR1CNR1ALDH1A1MAPTTSHR
	SCHEMBL2999629	0.82	NPSR1 (0.45)	NPSR1ALDH1A1MAPTTSHRKMT2A
	SCHEMBL2007303	0.81	PKM (0.57)	CNR1ALDH1A1TSHRKMT2AMEN1
	SCHEMBL2008868	0.81	CNR1 (0.52)	CNR1ALDH1A1TSHRKMT2AMEN1
	SCHEMBL3055176	0.81	CNR1 (0.47)	CNR1TSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.