Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258692 | 0.84 | PSMB8 (0.37) | HSD17B10ALDH1A1HPGDKMT2ARAB9A | |
| SCHEMBL18510196 | 0.82 | HPGD (0.44) | ALDH1A1HPGDKMT2AMEN1RAB9A | |
| SCHEMBL18510194 | 0.82 | HPGD (0.44) | ALDH1A1HPGDKMT2AMEN1RAB9A | |
| SCHEMBL20968628 | 0.81 | HPGD (0.36) | HSD17B10ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL18510177 | 0.80 | HPGD (0.45) | HSD17B10ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL18510191 | 0.80 | HPGD (0.45) | HSD17B10ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL18519268 | 0.80 | HPGD (0.45) | HSD17B10ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL31005443 | 0.75 | HPGD (0.43) | HSD17B10ALDH1A1HPGDRAB9APOLB | |
| SCHEMBL14273419 | 0.75 | HPGD (0.43) | HSD17B10ALDH1A1HPGDRAB9APOLB | |
| SCHEMBL23768443 | 0.75 | HPGD (0.33) | HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3912982-A1 | NOVEL HYDROPHILIC LINKERS AND LIGAND-DRUG CONJUGATES THEREOF | Hangzhou Dac Biotech Co., Ltd (CN) | 2021-11-24 | — | — | EP | disclosed |
| EP-3271329-B1 | NOVEL HYDROPHILIC LINKERS AND LIGAND-DRUG CONJUGATES THEREOF | HANGZHOU DAC BIOTECH CO LTD (CN) | 2021-08-18 | — | — | EP | disclosed |
| US-10456479-B2 | Hydrophilic linkers and ligand-drug conjugates thereof | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-10-29 | — | — | US | disclosed |
| US-20180110876-A1 | NOVEL HYDROPHILIC LINKERS AND LIGAND-DRUG CONJUGATES THEREOF | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10456479-B2 | Hydrophilic linkers and ligand-drug conjugates thereof | CD44, SELPLG, EPCAM | HSD17B10 997/4885ALDH1A1 1069/4885HPGD 1325/4885 |
| US-20180110876-A1 | NOVEL HYDROPHILIC LINKERS AND LIGAND-DRUG CONJUGATES THEREOF | CD44, HACD3, HACD2 | HSD17B10 1009/4885ALDH1A1 1285/4885HPGD 1722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.