Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20091602 | 0.81 | HSD17B10 (0.38) | HPGDALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL18510199 | 0.75 | HPGD (0.43) | HPGDALDH1A1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL20968651 | 0.75 | EPHX2 (0.32) | — | |
| SCHEMBL14524708 | 0.73 | HPGD (0.42) | HPGDALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL31348938 | 0.72 | HPGD (0.43) | HPGDALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL15459726 | 0.69 | HDAC3 (0.33) | PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL20968690 | 0.69 | TGM2 (0.33) | ALDH1A1TSHR | |
| SCHEMBL14984805 | 0.68 | ALDH1A1 (0.44) | HPGDALDH1A1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL18211081 | 0.67 | CYP1A2 (0.45) | HPGDALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL20968627 | 0.67 | OPRM1 (0.38) | HPGDALDH1A1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10646585-B2 | Hydrophilic linkers and ligand-drug conjugates thereof | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-05-12 | — | — | US | disclosed |
| US-20190125894-A1 | NOVEL HYDROPHILIC LINKERS AND LIGAND-DRUG CONJUGATES THEREOF | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190125894-A1 | NOVEL HYDROPHILIC LINKERS AND LIGAND-DRUG CONJUGATES THEREOF | CD44, HACD3, HACD2 | HPGD 1722/4885ALDH1A1 1285/4885KMT2A 1850/4885 |
| US-10646585-B2 | Hydrophilic linkers and ligand-drug conjugates thereof | CD44, SELPLG, EPCAM | HPGD 1325/4885ALDH1A1 1069/4885KMT2A 1987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.