Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | PARL | Q9H300 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10830933 | 0.86 | MEN1 (0.34) | PSMB8PSMB5KMT2A | |
| SCHEMBL18373366 | 0.85 | DDB1 (0.33) | PSMB8PSMB5 | |
| SCHEMBL8512365 | 0.85 | TSHR (0.38) | ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL12724593 | 0.84 | ALDH1A1 (0.34) | ALDH1A1PKMKMT2A | |
| SCHEMBL20091602 | 0.84 | HSD17B10 (0.38) | ALDH1A1HSD17B10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL43720 | 0.82 | TSHR (0.34) | PSMB8PSMB5MGLLLMNA | |
| SCHEMBL1634933 | 0.81 | — | — | |
| SCHEMBL42368 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTHSD17B10PKMNPC1 | |
| SCHEMBL29352062 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTHSD17B10PKMNPC1 | |
| SCHEMBL27271409 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTALOX12NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220211826-A1 | COMPOSITIONS AND METHODS FOR INDUCING IMMUNE TOLERANCE | UNIV CHICAGO (US) | 2022-07-07 | — | — | US | disclosed |
| US-11253579-B2 | Compositions and methods for inducing immune tolerance | THE UNIVERSITY OF CHICAGO (US) | 2022-02-22 | — | — | US | disclosed |
| US-20200237669-A1 | KIDNEY-TARGETING DRUG DELIVERY CARRIER | KYOTO PHARMACEUTICAL UNIVERSITY (JP) | 2020-07-30 | — | — | US | disclosed |
| EP-3650484-A1 | KIDNEY-TARGETING DRUG DELIVERY CARRIER | Kyoto Pharmaceutical University (JP) | 2020-05-13 | — | — | EP | disclosed |
| US-5395924-A | Oligosaccharide or glycopeptide bound to lectin and conjugated with cell binding agent, improved targeting of cells for cytolysis | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1995-03-07 | — | — | US | disclosed |
| US-5239062-A | Blocked lectins, methods and affinity support for making same using affinity ligands, and method of killing selected cell populations having reduced nonselective cytotoxicity | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1993-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11253579-B2 | Compositions and methods for inducing immune tolerance | CD47, LY96, CD74 | PSMB8 911/4885PSMB5 1472/4885ALDH1A1 2268/4885 |
| US-20220211826-A1 | COMPOSITIONS AND METHODS FOR INDUCING IMMUNE TOLERANCE | CD47, LY96, CD74 | PSMB8 911/4885PSMB5 1472/4885ALDH1A1 2268/4885 |
| US-20200237669-A1 | KIDNEY-TARGETING DRUG DELIVERY CARRIER | TIE1, MET, SLC2A8 | PSMB8 2192/4885PSMB5 2714/4885ALDH1A1 3707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.