Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | HTR6 | P50406 | 4/20 | 0.51 |
| ▸ | HTR1D | P28221 | 3/20 | 0.51 |
| ▸ | HTR7 | P34969 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24201870 | 0.85 | HSD17B10 (0.75) | HSD17B10TSHRSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7886752 | 0.84 | HTR1D (0.71) | HSD17B10TSHRSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4805847 | 0.84 | MEN1 (0.63) | HSD17B10TSHRSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL18509436 | 0.83 | POLB (0.66) | HSD17B10TSHRSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL21374161 | 0.83 | HTR7 (0.74) | HSD17B10TSHRSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL17357058 | 0.83 | HSD17B10 (0.59) | HSD17B10TSHRSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL18404931 | 0.83 | HSD17B10 (0.59) | HSD17B10TSHRSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6235393 | 0.81 | HTR6 (0.73) | HSD17B10SMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL25082463 | 0.81 | HSD17B10 (0.56) | HSD17B10SMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL26227993 | 0.81 | HSD17B10 (0.56) | HSD17B10TSHRSMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018073828-A1 | DNA PRIMASE AND GYRASE INHIBITORS | B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) | 2018-04-26 | — | — | WO | disclosed |