Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.75 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20094577 | 0.85 | HSD17B10 (0.62) | HSD17B10SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL12090866 | 0.83 | HSD17B10 (0.54) | HSD17B10SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL3116596 | 0.81 | HSD17B10 (0.53) | HSD17B10SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL24358704 | 0.81 | HTR6 (0.65) | HSD17B10SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL19192790 | 0.81 | SMN1; SMN2 (0.53) | HSD17B10SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL26227993 | 0.80 | HSD17B10 (0.56) | HSD17B10SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL7886752 | 0.80 | HTR1D (0.71) | HSD17B10SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL10067045 | 0.80 | HSD17B10 (0.55) | HSD17B10SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL18509436 | 0.79 | POLB (0.66) | HSD17B10SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL146647 | 0.79 | HSD17B10 (0.50) | HSD17B10SMN1; SMN2MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017513-A1 | AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE | SHANGHAI JEMINCARE PHARMACEUTICALS CO., LTD (CN) | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017513-A1 | AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE | S1PR1, S1PR2, S1PR3 | HSD17B10 3238/4885SMN1; SMN2 4722/4885MAPT 4417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.