Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21109951 | 0.83 | MAOB (0.47) | MAOBMAOACYP1A2TNKSPARP1 | |
| SCHEMBL21109946 | 0.82 | MAPT (0.43) | TNKSTNKS2MAPTHPGDALDH1A1 | |
| SCHEMBL26529714 | 0.79 | ALDH1A1 (0.47) | CYP1A2MAPTHPGDALDH1A1KDM4E | |
| SCHEMBL19292713 | 0.78 | MAOB (0.40) | MAOBMAOACYP1A2TNKSPARP1 | |
| SCHEMBL20987510 | 0.77 | ALOX5 (0.54) | MAOBMAOATNKSPARP1TNKS2 | |
| SCHEMBL19110126 | 0.76 | MAPT (0.35) | CYP1A2AHRMAPTHPGDALDH1A1 | |
| SCHEMBL18597136 | 0.76 | MAPT (0.47) | MAOAAHRMAPTHPGDALDH1A1 | |
| SCHEMBL23426917 | 0.76 | MAPT (0.41) | MAOACYP1A2AHRMAPTHPGD | |
| SCHEMBL23426915 | 0.76 | AHR (0.41) | MAOBMAOAAHRMAPTHPGD | |
| SCHEMBL19743192 | 0.76 | PDE10A (0.38) | MAOBMAOACYP1A2AHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180114922-A1 | COMPOUND AND PREPARATION METHOD THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE | BOE TECHNOLOGY GROUP CO. LTD. (CN) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180114922-A1 | COMPOUND AND PREPARATION METHOD THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE | LEF1, TYR, LSS | MAOB 39/4885MAOA 74/4885CYP1A2 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.