SCHEMBL2009581

SCHEMBL2009581

O=C(Cl)c1ccc(C(=O)c2ccc(C(=O)Cl)c(C(=O)Cl)c2C(=O)Cl)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
SRD5A2 P31213 3/20 0.37
NR4A1 P22736 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 2/20 0.34
LMNA P02545 2/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
PKM P14618 1/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
LIG1 P18858 1/20 0.34
RAB9A P51151 1/20 0.34
CDC25B P30305 2/20 0.33
CDC25A P30304 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ATM Q13315 1/20 0.33
AKR1C3 P42330 1/20 0.33
MAPK1 P28482 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8904804 0.82 ALDH1A1 (0.48) ALDH1A1KDM4EMAPTALOX15
SCHEMBL30956653 0.79 ALDH1A1 (0.36) ALDH1A1SRD5A2HSD17B10ALOX15
SCHEMBL8925670 0.77 SRD5A2 (0.40) ALDH1A1SRD5A2NR4A1KDM4EMAPT
SCHEMBL894684 0.77 SRD5A2 (0.55) ALDH1A1SRD5A2MAPTLMNAESR1
SCHEMBL9622204 0.76 AKR1C3 (0.53) ALDH1A1SRD5A2NR4A1MAPTPKM
Hydrochloric Acid SCHEMBL25180346 0.74 SRD5A2 (0.52) ALDH1A1SRD5A2MAPTLMNAESR1
SCHEMBL20587670 0.74 ALDH1A1 (0.59) ALDH1A1SRD5A2MAPTLMNAESR1
SCHEMBL68148 0.74 ALDH1A1 (0.59) ALDH1A1SRD5A2MAPTLMNAESR1
SCHEMBL5034945 0.72 CDC25A (0.40) ALDH1A1SRD5A2NR4A1KDM4EMAPT
SCHEMBL10800604 0.71 ALDH1A1 (0.50) ALDH1A1NR4A1MAPTCDC25BAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257619-A1 GRAFT COPOLYMERS FOR REDUCING SURFACE TENSION IN POLYMER BLENDS Covestro Deutschland AG (DE) 2023-10-11 EP disclosed
EP-4153680-A1 POLYCARBONATE BLEND HAVING REDUCED DISTURBING NOISE Covestro Deutschland AG (DE) 2023-03-29 EP disclosed
EP-4025580-A1 POLYPHOSPHAZENE AND MOLDING COMPOUND CONTAINING THE POLYPHOSPHAZENE Covestro Intellectual Property GmbH & Co. KG (DE) 2022-07-13 EP disclosed
EP-4021977-A1 FLAME-RETARDANT POLYCARBONATE COMPOSITION AND MOLDED PARTS AS WELL AS ARTICLES MADE THEREFROM Covestro Intellectual Property GmbH & Co. KG (DE) 2022-07-06 EP disclosed
WO-2021138113-A1 CHEMICAL RESISTANT POLYCARBONATE BLEND COMPOSITIONS COVESTRO LLC (US) 2021-07-08 WO disclosed
WO-2021110550-A1 FLAME RETARDANT IMPACT-MODIFIED POLYCARBONATE COMPOSITION COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-06-10 WO disclosed
WO-2021105008-A1 FLAME-RESISTANT POLYCARBONATE-POLYESTER BLEND COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-06-03 WO disclosed
WO-2021043654-A1 POLYPHOSPHAZENE AND MOLDING COMPOUND CONTAINING THE POLYPHOSPHAZENE COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-03-11 WO disclosed
WO-2021037705-A1 FLAME-RETARDANT POLYCARBONATE COMPOSITION AND MOLDED PARTS AS WELL AS ARTICLES MADE THEREFROM COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-03-04 WO disclosed
EP-3728469-A1 THERMOPLASTIC COMPOSITIONS WITH GOOD STABILITY Covestro Deutschland AG (DE) 2020-10-28 EP disclosed
WO-2007075365-A2 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS GENERAL ELECTRIC COMPANY (US) 2007-07-05 WO disclosed
US-20070083026-A1 Polyarylate-siloxane copolymers GENERAL ELECTRIC COMPANY (US) 2007-04-12 US disclosed
EP-1554333-A1 METHOD AND APPARATUS TO MAKE HIGH MOLECULAR WEIGHT MELT POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2005-07-20 EP disclosed
US-6831120-B1 With graft polymer, phosphonate amine and inorganic powder BAYER AKTIENGESELLSCHAFT (DE) 2004-12-14 US disclosed
WO-2004033531-A1 METHOD AND APPARATUS TO MAKE HIGH MOLECULAR WEIGHT MELT POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-04-22 WO disclosed
US-20020147261-A1 Impact-modified polycarbonate compositions BAYER AKTIENGESELLSCHAFT (DE) 2002-10-10 US disclosed
EP-1187867-A1 THERMALLY STABLE POLYMERS, METHOD OF PREPARATION, AND ARTICLES MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2002-03-20 EP disclosed
WO-2000069945-A1 THERMALLY STABLE POLYMERS, METHOD OF PREPARATION, AND ARTICLES MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2000-11-23 WO disclosed
US-5635560-A THERMOPLASTIC MOLDING MATERIALS; IMPACT STRENGTH, NONCRACKING, MOLD RELEASING BAYER AG (DE) 1997-06-03 US disclosed
US-4645806-A MOLDING MATERIALS, ENGINEERING THERMOPLASTICS BAYER AKTIENGESELLSCHAFT (DE) 1987-02-24 US disclosed