Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338194 | 0.81 | TDP1 (0.48) | CDC25ACDC25BHSD17B10SRD5A2POLB | |
| SCHEMBL29440655 | 0.75 | ALDH1A1 (0.40) | CDC25ACDC25BHSD17B10SRD5A2POLB | |
| SCHEMBL75886 | 0.75 | ALDH1A1 (0.40) | CDC25ACDC25BHSD17B10SRD5A2POLB | |
| SCHEMBL2009581 | 0.72 | ALDH1A1 (0.39) | CDC25ACDC25BHSD17B10SRD5A2KDM4E | |
| SCHEMBL9197919 | 0.71 | ALDH1A1 (0.48) | HSD17B10TDP1KDM4EALDH1A1MAPT | |
| SCHEMBL6560811 | 0.71 | KDM4E (0.52) | CDC25ACDC25BHSD17B10SRD5A2POLB | |
| SCHEMBL8904804 | 0.70 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL7707415 | 0.67 | ALDH1A1 (0.54) | HSD17B10POLBTDP1KDM4EALDH1A1 | |
| SCHEMBL9815475 | 0.67 | KDM4E (0.50) | HSD17B10TDP1KDM4EALDH1A1MAPT | |
| SCHEMBL654794 | 0.66 | ALDH1A1 (0.52) | HSD17B10SRD5A2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511754-B1 | MULTIMER FORMS OF MONO- AND BIS-ACYLPHOSPHINE OXIDES | CIBA HOLDING INC (CH) | 2008-07-23 | — | — | EP | disclosed |