SCHEMBL20587670

SCHEMBL20587670

O=C(Cl)c1ccc(C(=O)Cl)cc1.O=C(Cl)c1ccc(C(=O)Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
TSHR P16473 3/20 0.47
TP53 P04637 1/20 0.47
CES2 O00748 6/20 0.45
CES1 P23141 6/20 0.45
ALOX15 P16050 1/20 0.43
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
LMNA P02545 2/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
SRD5A2 P31213 1/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40
NAPRT Q6XQN6 1/20 0.40
CA12 O43570 1/20 0.38
CA3 P07451 1/20 0.38
TYR P14679 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68148 1.00 ALDH1A1 (0.59) ALDH1A1TSHRTP53CES2CES1
SCHEMBL28787222 0.96 ALDH1A1 (0.56) ALDH1A1TSHRTP53CES2CES1
Hydrogen Sulfide SCHEMBL10896015 0.96 ALDH1A1 (0.56) ALDH1A1TSHRTP53CES2CES1
Hydrochloric Acid SCHEMBL2362644 0.96 ALDH1A1 (0.56) ALDH1A1TSHRTP53CES2CES1
SCHEMBL6758498 0.96 ALDH1A1 (0.64) ALDH1A1TSHRTP53CES2CES1
Ammonia Solution, Strong SCHEMBL2023211 0.96 ALDH1A1 (0.56) ALDH1A1TSHRTP53CES2CES1
Benzene SCHEMBL10386399 0.93 ALDH1A1 (0.54) ALDH1A1TSHRTP53CES2CES1
SCHEMBL11417369 0.90 CES2 (0.60) ALDH1A1TSHRTP53CES2CES1
SCHEMBL10670934 0.90 ALDH1A1 (0.52) ALDH1A1TSHRTP53CES2CES1
Carbon Tetrachloride SCHEMBL28375538 0.90 ALDH1A1 (0.52) ALDH1A1TSHRTP53CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3638654-A1 MELT ADDITIVE COMPOUNDS, METHODS OF USING THE SAME, AND ARTICLES AND COMPOSITIONS INCLUDING THE SAME 3M Innovative Properties Company (US) 2020-04-22 EP disclosed
WO-2018229596-A1 MELT ADDITIVE COMPOUNDS, METHODS OF USING THE SAME, AND ARTICLES AND COMPOSITIONS INCLUDING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-12-20 WO disclosed