Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 2/20 | 0.39 |
| ▸ | LTK | P29376 | 2/20 | 0.39 |
| ▸ | GRK5 | P34947 | 2/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | CDK7 | P50613 | 2/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20096657 | 0.75 | YTHDC1 (0.38) | MAP4K4CLK4CSF1R | |
| SCHEMBL14580328 | 0.70 | KDM4E (0.35) | KDRLIMK1LRRK2CHEK1DAPK3 | |
| SCHEMBL23815922 | 0.69 | ADORA2A (0.33) | KDRLIMK1LRRK2CHEK1DAPK3 | |
| SCHEMBL23892134 | 0.66 | CDK2 (0.47) | PRKACA | |
| SCHEMBL19417814 | 0.62 | HRH4 (0.37) | — | |
| SCHEMBL29044216 | 0.62 | ADORA2A (0.36) | KDRLIMK1LRRK2CHEK1DAPK3 | |
| SCHEMBL19204413 | 0.61 | NOS1 (0.47) | — | |
| SCHEMBL24954034 | 0.60 | KDR (0.40) | KDRLIMK1LRRK2CHEK1DAPK3 | |
| SCHEMBL30159493 | 0.60 | KDR (0.40) | KDRLIMK1LRRK2CHEK1DAPK3 | |
| Vitamin B4 SCHEMBL4257555 | 0.60 | KDR (0.43) | KDRLIMK1LRRK2CHEK1DAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |