Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.39 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.38 |
| ▸ | GMPS | P49915 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | AHCY | P23526 | 3/20 | 0.37 |
| ▸ | PI4KA | P42356 | 3/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21311159 | 0.81 | HTT (0.46) | METTL3METTL14ADORA2AGMPSADORA3 | |
| SCHEMBL21311154 | 0.80 | ADORA3 (0.47) | ADORA2AGMPSADORA3SLC28A1ADORA1 | |
| SCHEMBL21311216 | 0.78 | ADORA2A (0.47) | ADORA2AGMPSADORA3SLC28A1ADORA1 | |
| SCHEMBL25521510 | 0.78 | ADORA3 (0.53) | ADORA2AGMPSADORA3SLC28A1ADORA1 | |
| SCHEMBL23025515 | 0.78 | ADORA3 (0.53) | ADORA2AGMPSADORA3SLC28A1ADORA1 | |
| SCHEMBL20097209 | 0.78 | ADORA2A (0.35) | METTL3METTL14ADORA2AGMPSADORA3 | |
| SCHEMBL21311217 | 0.77 | ADORA2A (0.47) | ADORA2AGMPSADORA3SLC28A1ADORA1 | |
| SCHEMBL21311468 | 0.77 | ALDH1A1 (0.39) | ADORA2AGMPSADORA3SLC28A1ALDH1A1 | |
| SCHEMBL21311388 | 0.77 | DOT1L (0.41) | ADORA2AGMPSADORA3SLC28A1AHCY | |
| SCHEMBL20097205 | 0.76 | ADORA2A (0.36) | ADORA2AGMPSADORA3SLC28A1AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |