Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.70 |
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.70 |
| ▸ | TP53 | P04637 | 3/20 | 0.70 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | MITF | O75030 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.51 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.51 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.51 |
| ▸ | GAPDH | P04406 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21311164 | 0.88 | ADORA3 (0.70) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| SCHEMBL21311225 | 0.87 | DOT1L (0.54) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| SCHEMBL21311165 | 0.85 | DOT1L (0.69) | ADORA3SLC29A1SMN1; SMN2DOT1LATM | |
| SCHEMBL20097049 | 0.84 | ADORA3 (0.51) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| Kinetin Riboside SCHEMBL14713232 | 0.83 | ADORA3 (1.00) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| Kinetin Riboside SCHEMBL14713468 | 0.83 | ADORA3 (1.00) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| Kinetin Riboside SCHEMBL217034 | 0.83 | ADORA3 (1.00) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| Kinetin Riboside SCHEMBL19583061 | 0.83 | ADORA3 (1.00) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| Kinetin Riboside SCHEMBL3190252 | 0.83 | ADORA3 (1.00) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| Kinetin Riboside SCHEMBL3339041 | 0.83 | ADORA3 (1.00) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |