Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AHCY | P23526 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20097018 | 0.84 | ADORA3 (0.70) | ADORA3TP53PAX8SLC29A1SMN1; SMN2 | |
| SCHEMBL21311158 | 0.80 | HTT (0.41) | ADORA3TP53PAX8SLC29A1SMN1; SMN2 | |
| SCHEMBL20097216 | 0.77 | DOT1L (0.58) | DOT1LAHCY | |
| SCHEMBL20096666 | 0.75 | DOT1L (0.56) | ADORA3DOT1LAHCYADORA1 | |
| SCHEMBL6890018 | 0.75 | ADORA3 (0.72) | ADORA3TP53SLC29A1TDP1ADORA2A | |
| SCHEMBL20096659 | 0.74 | AHCY (0.55) | ADORA3SLC29A1SMN1; SMN2DOT1LAHCY | |
| SCHEMBL21311164 | 0.74 | ADORA3 (0.70) | ADORA3TP53PAX8SLC29A1SMN1; SMN2 | |
| SCHEMBL5961364 | 0.74 | PDE2A (0.64) | ADORA3SLC29A1SMN1; SMN2DOT1LAHCY | |
| SCHEMBL11427985 | 0.74 | PDE2A (0.64) | ADORA3SLC29A1SMN1; SMN2DOT1LAHCY | |
| SCHEMBL21311159 | 0.72 | HTT (0.46) | ADORA3TP53PAX8SLC29A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |