Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20096659 | 0.85 | AHCY (0.55) | AHCYP2RY12PDE2ADOT1LADORA1 | |
| SCHEMBL5961364 | 0.84 | PDE2A (0.64) | AHCYP2RY12PDE2ADOT1LADORA1 | |
| SCHEMBL11427985 | 0.84 | PDE2A (0.64) | AHCYP2RY12PDE2ADOT1LADORA1 | |
| SCHEMBL6896076 | 0.80 | ADORA1 (0.66) | AHCYALDH1A1HIF1ADOT1LADORA1 | |
| SCHEMBL6896080 | 0.80 | ADORA1 (0.66) | AHCYALDH1A1HIF1ADOT1LADORA1 | |
| SCHEMBL20097216 | 0.79 | DOT1L (0.58) | AHCYDOT1LP2RX3P2RX4P2RX2 | |
| SCHEMBL14429057 | 0.79 | PDE2A (0.59) | AHCYP2RY12PDE2ADOT1LADORA1 | |
| SCHEMBL19927540 | 0.78 | AHCY (0.53) | AHCYALDH1A1HIF1AP2RY12DOT1L | |
| SCHEMBL21565155 | 0.78 | AHCY (0.53) | AHCYALDH1A1HIF1AP2RY12DOT1L | |
| SCHEMBL19927503 | 0.78 | AHCY (0.69) | AHCYALDH1A1HIF1ADOT1LADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |