Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.58 |
| ▸ | AHCY | P23526 | 3/20 | 0.55 |
| ▸ | GNMT | Q14749 | 1/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20096666 | 0.93 | DOT1L (0.56) | DOT1LAHCYNT5ECARM1 | |
| SCHEMBL20096659 | 0.84 | AHCY (0.55) | DOT1LAHCYNT5E | |
| SCHEMBL11427985 | 0.83 | PDE2A (0.64) | DOT1LAHCYNT5EP2RX3P2RX4 | |
| SCHEMBL5961364 | 0.83 | PDE2A (0.64) | DOT1LAHCYNT5EP2RX3P2RX4 | |
| SCHEMBL6896080 | 0.80 | ADORA1 (0.66) | DOT1LAHCY | |
| SCHEMBL6896076 | 0.80 | ADORA1 (0.66) | DOT1LAHCY | |
| SCHEMBL20097048 | 0.79 | AHCY (0.62) | DOT1LAHCYNT5EP2RX3P2RX4 | |
| SCHEMBL5847481 | 0.78 | P2RX3 (0.74) | P2RX3P2RX4P2RX2 | |
| SCHEMBL14428965 | 0.77 | PDE2A (0.59) | DOT1LAHCYNT5E | |
| SCHEMBL14429057 | 0.77 | PDE2A (0.59) | DOT1LAHCYNT5EP2RX3P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |