Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 5/20 | 0.68 |
| ▸ | CDK1 | P06493 | 5/20 | 0.68 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.68 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21311333 | 0.88 | CCNB2 (0.65) | CCNB2CDK1CCNB1CCNB3HTT | |
| SCHEMBL20097149 | 0.81 | CCNB2 (1.00) | CCNB2CDK1CCNB1CCNB3HTT | |
| SCHEMBL20119629 | 0.79 | CDK1 (0.72) | CCNB2CDK1CCNB1CCNB3HTT | |
| SCHEMBL20097160 | 0.78 | CCNB2 (0.69) | CCNB2CDK1CCNB1CCNB3HTT | |
| SCHEMBL20097047 | 0.77 | CCNB2 (0.65) | CCNB2CDK1CCNB1CCNB3HTT | |
| SCHEMBL20119633 | 0.76 | HTT (0.67) | CCNB2CDK1CCNB1CCNB3HTT | |
| SCHEMBL31711715 | 0.75 | CCNB2 (0.66) | CCNB2CDK1CCNB1CCNB3HTT | |
| SCHEMBL31711714 | 0.75 | HTT (0.66) | CCNB2CDK1CCNB1CCNB3HTT | |
| SCHEMBL63354 | 0.74 | CDK1 (0.61) | CCNB2CDK1CCNB1CCNB3HTT | |
| SCHEMBL457250 | 0.73 | HTT (0.67) | CCNB2CDK1CCNB1CCNB3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |