Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 11/20 | 1.00 |
| ▸ | CDK1 | P06493 | 11/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 11/20 | 1.00 |
| ▸ | CCNB3 | Q8WWL7 | 11/20 | 1.00 |
| ▸ | CDK2 | P24941 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.56 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.56 |
| ▸ | CDK7 | P50613 | 1/20 | 0.56 |
| ▸ | CCNH | P51946 | 1/20 | 0.56 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20119629 | 0.84 | CDK1 (0.72) | CCNB2CDK1CCNB1CCNB3HTT | |
| SCHEMBL20097160 | 0.82 | CCNB2 (0.69) | CCNB2CDK1CCNB1CCNB3HTT | |
| SCHEMBL20097147 | 0.81 | CCNB2 (0.68) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL754120 | 0.80 | CDK1 (1.00) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL30539284 | 0.80 | CDK1 (1.00) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL31711715 | 0.79 | CCNB2 (0.66) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL31711714 | 0.79 | HTT (0.66) | CCNB2CDK1CCNB1CCNB3HTT | |
| SCHEMBL21311333 | 0.79 | CCNB2 (0.65) | CCNB2CDK1CCNB1CCNB3HTT | |
| SCHEMBL20097047 | 0.79 | CCNB2 (0.65) | CCNB2CDK1CCNB1CCNB3HTT | |
| SCHEMBL457250 | 0.78 | HTT (0.67) | CCNB2CDK1CCNB1CCNB3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-08-29 | — | — | US | disclosed |
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | POLRMT, EIF2AK2, NSUN3 | CCNB2 4302/4885CDK1 4187/4885CCNB1 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.