Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18626505 | 0.83 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTMC4RLMNA | |
| SCHEMBL14791995 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPTMC4RLMNA | |
| SCHEMBL2935699 | 0.79 | GAA (0.52) | KDM4EALDH1A1MAPTMC4RLMNA | |
| SCHEMBL9610929 | 0.79 | ALDH1A1 (0.45) | KDM4EALDH1A1MAPTMC4RLMNA | |
| SCHEMBL9610928 | 0.78 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTMC4RLMNA | |
| SCHEMBL12830614 | 0.77 | MC4R (0.65) | KDM4EALDH1A1MC4RLMNACHKA | |
| SCHEMBL1367503 | 0.76 | SMN1; SMN2 (0.70) | KDM4EMC4RLMNASMN1; SMN2POLB | |
| SCHEMBL306744 | 0.76 | LMNA (0.69) | KDM4EALDH1A1MC4RLMNASMN1; SMN2 | |
| SCHEMBL14228427 | 0.75 | HRH3 (0.54) | KDM4EALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL112800 | 0.75 | MC4R (0.47) | KDM4EALDH1A1MAPTMC4RLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075858-A1 | METHODS OF USING INDAZOLE-3-CARBOXAMIDES AND THEIR USE AS WNT/B-CATENIN SIGNALING PATHWAY INHIBITORS | SAMUMED, LLC (US) | 2018-04-26 | — | — | WO | disclosed |