SCHEMBL2009761

SCHEMBL2009761

CCCCCCCCCC(=O)OCCS

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.77
DNM1 Q05193 1/20 0.68
PAM P19021 2/20 0.58
TSHR P16473 1/20 0.55
MAPT P10636 1/20 0.55
PRSS1 P07477 1/20 0.54
PRSS2 P07478 1/20 0.54
PRSS3 P35030 1/20 0.54
NAAA Q02083 1/20 0.53
LMNA P02545 4/20 0.53
ALDH1A1 P00352 1/20 0.53
KDM4E B2RXH2 1/20 0.51
DUSP3 P51452 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
HTR2C P28335 1/20 0.51
PRKCA P17252 1/20 0.49
PRKCE Q02156 1/20 0.49
PRKCQ Q04759 1/20 0.49
PRKCD Q05655 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5995602 1.00 DGKA (0.77) DGKADNM1PAMTSHRMAPT
SCHEMBL6442472 1.00 DGKA (0.77) DGKADNM1PAMTSHRMAPT
SCHEMBL1487523 1.00 DGKA (0.77) DGKADNM1PAMTSHRMAPT
SCHEMBL7946428 1.00 DGKA (0.77) DGKADNM1PAMTSHRMAPT
SCHEMBL6440290 1.00 DGKA (0.77) DGKADNM1PAMTSHRMAPT
SCHEMBL2254720 1.00 DGKA (0.77) DGKADNM1PAMTSHRMAPT
SCHEMBL1251319 1.00 DGKA (0.77) DGKADNM1PAMTSHRMAPT
SCHEMBL6441893 1.00 DGKA (0.77) DGKADNM1PAMTSHRMAPT
SCHEMBL5993730 1.00 DGKA (0.77) DGKADNM1PAMTSHRMAPT
SCHEMBL11118880 0.98 DGKA (0.74) DGKADNM1PAMTSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0178115-B1 PROCESS FOR THE PRODUCTION OF HEAT RESISTANT METHACRYLIC RESIN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-07-19 EP claimed
US-4661571-A RADICAL POLYMERIZATION OF METHYL METHACRYLATE AND VINYL MONOMER IN PRESENCE OF CHAIN TRANSFER AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-04-28 US claimed
EP-0178115-A2 Process for the production of heat resistant methacrylic resin SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-04-16 EP claimed
EP-2507331-B1 POLYMER, PROCESS AND COMPOSITION DSM IP ASSETS BV (NL) 2014-08-06 EP disclosed
US-20120301686-A1 POLYMER, PROCESS AND COMPOSITION DSM IP ASSETS B.V. (NL) 2012-11-29 US disclosed
EP-2507331-A1 POLYMER, PROCESS AND COMPOSITION DSM IP Assets B.V. (NL) 2012-10-10 EP disclosed
US-7994152-B2 Method of treating a cancer by administering A 2′,5′-oligoadenylate analog SANKYO COMPANY, LIMITED (JP) 2011-08-09 US disclosed
WO-2011067375-A1 POLYMER, PROCESS AND COMPOSITION DSM IP ASSETS B.V. (NL) 2011-06-09 WO disclosed
US-20100035976-A1 Method of treating a tumor or a viral disease by administering a 2' , 5' -oligoadenylate analog SANKYO COMPANY, LIMITED (JP) 2010-02-11 US disclosed
US-7651999-B2 phosphorothioate modification containg oligonadenylates useful as antiviral, anticarcinogenic and antitumor agent; stable and have superior activity for treating lung cancer SANKYO COMPANY, LIMITED (JP) 2010-01-26 US disclosed
EP-1342749-B1 Organic based thermal stabilizers and heat stabilized polymer compositions ROHM & HAAS (US) 2007-11-21 EP disclosed
US-4711920-A HEAT AND RADIATION RESISTANCE; WEATHERPROOFING; NONIRRITATING TO EYES AND MUCUS MEMBRANES MORTON THIOKOL, INC. (US) 1987-12-08 US disclosed
US-4661571-A RADICAL POLYMERIZATION OF METHYL METHACRYLATE AND VINYL MONOMER IN PRESENCE OF CHAIN TRANSFER AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-04-28 US disclosed
EP-0178115-A2 Process for the production of heat resistant methacrylic resin SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-04-16 EP disclosed
US-RE30810-E HEAT STABILIZERS FOR POLYMERS THIOKOL CORPORATION (US) 1981-12-01 US disclosed
US-4179432-A 2-HYDROXYBENZOPHENONE, ORGANOTIN MERCAPTIDE PHOTOSTABILITY CINCINNATI MILACRON CHEMICALS, INC. (US) 1979-12-18 US disclosed
US-RE30032-E POLYMER STABILIZERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1979-06-12 US disclosed
US-4120845-A FOR VINYL OR VINYLIDENE HALIDE POLYMERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1978-10-17 US disclosed
US-4062881-A POLYVINYL CHLORIDE CINCINNATI MILACRON CHEMICALS, INC. (US) 1977-12-13 US disclosed
US-3979359-A STABILIZERS FOR VINYL- AND VINYLIDENE HALIDE POLYMERS CINCINNATI MILACRON CHEMICALS, INC. (US) 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035976-A1 Method of treating a tumor or a viral disease by administering a 2' , 5' -oligoadenylate analog ADAR, NSUN2, ADORA3 DGKA 3822/4885DNM1 1887/4885PAM 78/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.