Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30197915 | 0.90 | HSD17B10 (0.52) | HSD17B10HPGDTSHRMAPK1CASP1 | |
| SCHEMBL14234676 | 0.90 | HSD17B10 (0.52) | HSD17B10HPGDTSHRMAPK1CASP1 | |
| SCHEMBL14769312 | 0.80 | SIRT1 (0.46) | HSD17B10HPGDTSHRMAPK1CASP1 | |
| SCHEMBL31046816 | 0.76 | TSHR (0.41) | HSD17B10HPGDTSHRMAPK1CASP1 | |
| SCHEMBL16233577 | 0.75 | CYP3A4 (0.47) | HSD17B10HPGDTSHRMAPK1CASP1 | |
| SCHEMBL11155205 | 0.71 | HSD17B10 (0.59) | HSD17B10HPGDTSHRMAPK1CASP1 | |
| SCHEMBL11055181 | 0.69 | ALDH1A1 (0.41) | HSD17B10HPGDTSHRMAPK1CASP1 | |
| SCHEMBL29433374 | 0.69 | HSD17B10 (0.44) | HSD17B10HPGDTSHRMAPK1CASP1 | |
| SCHEMBL2811005 | 0.68 | GAA (0.50) | HSD17B10HPGDTSHRCASP1THRB | |
| SCHEMBL11655514 | 0.68 | ACLY (0.49) | HSD17B10HPGDTSHRMAPK1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957484-B2 | Methods for promoting cell reprogramming | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2018-05-01 | — | — | US | disclosed |