Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20098769 | 0.83 | CDC25A (0.40) | CDC25ACDC25BGRIN2DGRIN3BGRIN1 | |
| SCHEMBL16465675 | 0.78 | ALOX5 (0.56) | ALDH1A1CYP2C9CYP2C19KDM4EKMT2A | |
| SCHEMBL18921848 | 0.73 | CYP1A2 (0.58) | CDC25ACDC25BALDH1A1APAF1CYP1A2 | |
| SCHEMBL16466025 | 0.64 | ALOX5 (0.64) | ALDH1A1APAF1CYP2C9CYP2C19KDM4E | |
| SCHEMBL18921820 | 0.64 | CYP1A2 (0.61) | CDC25ACDC25BALDH1A1APAF1CYP1A2 | |
| SCHEMBL23794429 | 0.63 | MAPT (0.57) | ALDH1A1GAALMNAKDM4EKMT2A | |
| SCHEMBL13894166 | 0.62 | HDAC3 (0.50) | ALDH1A1GAACYP1A2LMNACYP2C9 | |
| SCHEMBL5848939 | 0.60 | ALDH1A1 (0.56) | CDC25ACDC25BGRIN2DGRIN3BGRIN1 | |
| SCHEMBL13948424 | 0.60 | MAPT (0.60) | CDC25ACDC25BALDH1A1KDM4EKMT2A | |
| SCHEMBL2177141 | 0.59 | ALDH1A1 (0.64) | CDC25ACDC25BALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957214-B2 | Multifunctional radical quenchers | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-05-01 | — | — | US | disclosed |