Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 19/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20098857 | 0.89 | NTRK1 (0.37) | NTRK1IRAK4 | |
| SCHEMBL20098872 | 0.82 | NTRK1 (0.39) | NTRK1 | |
| SCHEMBL14897027 | 0.81 | NTRK1 (0.43) | NTRK1IRAK4 | |
| SCHEMBL18655146 | 0.81 | NTRK1 (0.43) | NTRK1IRAK4 | |
| SCHEMBL14897293 | 0.75 | IRAK4 (0.49) | NTRK1IRAK4 | |
| SCHEMBL14897269 | 0.75 | IRAK4 (0.49) | NTRK1IRAK4 | |
| SCHEMBL14882121 | 0.73 | NTRK1 (0.44) | NTRK1IRAK4 | |
| SCHEMBL14882125 | 0.73 | NTRK1 (0.44) | NTRK1IRAK4 | |
| SCHEMBL21765939 | 0.73 | PDE10A (0.44) | NTRK1IRAK4 | |
| SCHEMBL18655256 | 0.72 | TGFBR1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957271-B2 | Substituted bicyclic aza-heterocycles and analogues as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2018-05-01 | — | — | US | disclosed |