SCHEMBL249822

SCHEMBL249822

O=c1ccn([C@@]2(I)C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.44
SLC28A2 O43868 1/20 0.44
SLC29A1 Q99808 1/20 0.44
SLC28A3 Q9HAS3 1/20 0.44
P2RY6 Q15077 9/20 0.39
TK1 P04183 1/20 0.34
P2RY14 Q15391 1/20 0.34
DUT P33316 2/20 0.33
P2RY2 P41231 2/20 0.33
P2RY4 P51582 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27451524 1.00 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL51723 0.84 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL28786348 0.84 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL9805678 0.83 P2RY6 (0.50) P2RY6DUTP2RY2P2RY4
Hydrochloric Acid SCHEMBL27782735 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL414705 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL27703606 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2242410 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL65485 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2009955 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2959 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630593-B2 Method of killing leukemia cells by administration of recombinant'Y3 proteins UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2026-05-19 US claimed
EP-4558641-A1 METHODS FOR DETECTION AND REDUCTION OF SAMPLE PREPARATION-INDUCED METHYLATION ARTIFACTS Guardant Health, Inc. (US) 2025-05-28 EP claimed
CN-119923475-A Method for detecting and reducing sample preparation induced methylation artifacts 夸登特健康公司 2025-05-02 CN claimed
EP-4086250-B1 MULTIFUNCTIONAL INHIBITORS OF MEK/PI3K AND MTOR/MEK/PI3K BIOLOGICAL PATHWAYS AND THERAPEUTIC METHODS USING THE SAME UNIV MICHIGAN REGENTS (US) 2024-12-11 EP claimed
CN-118488841-A Combination of PRMT5 inhibitor and anticancer therapeutic agent 南京再明医药有限公司 2024-08-13 CN claimed
WO-2024020573-A1 METHODS FOR DETECTION AND REDUCTION OF SAMPLE PREPARATION-INDUCED METHYLATION ARTIFACTS GUARDANT HEALTH, INC. (US) 2024-01-25 WO claimed
WO-2023225608-A1 METHODS FOR ABLATING MYELOID DERIVED SUPPRESSOR CELLS USING NEO-201 ANTIBODY PRECISION BIOLOGICS, INC. (US) 2023-11-23 WO claimed
US-20230272019-A1 FUNGAL GLYCAN BINDING PROTEIN WHICH POSSESSES ANTIVIRAL AND ANTICANCER ACTIVITY UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-08-31 US claimed
CN-116407503-A Blank liposome composition with pentacyclic triterpene compound as membrane material, and preparation method and application thereof 复旦大学 2023-07-11 CN claimed
US-20230110614-A1 HEPARIN AND N-ACETYLCYSTEINE FOR THE TREATMENT OF A RESPIRATORY VIRUS ATOSSA THERAPEUTICS, INC. 2023-04-13 US claimed
WO-1987001935-A1 TRANSDERMAL AND SYSTEMIC PREPARATION AND METHOD RAJADHYAKSHA VITHAL J 1987-04-09 WO claimed
US-4585736-A Flow cytometric measurement of total DNA and incorporated halodeoxyuridine THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1986-04-29 US claimed
US-4444762-A Vehicle composition containing 1-substituted azacyclopentan-2-ones NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1984-04-24 US claimed
US-4424210-A Vehicle composition containing 1-substituted azacycloalkan-2-ones NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1984-01-03 US claimed
US-4423040-A Vehicle composition containing 1-substituted azacyclohexan-2-ones NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1983-12-27 US claimed
US-4415563-A TOPICAL APPLICATION OF MEDICINE; COSMETICS NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1983-11-15 US claimed
US-4316893-A USED FOR TOPICAL APPLICATION WITH A PHYSIOLOGICALLY ACTIVE AGENT NELSON RESEARCH & DEVELOPMENT CO. (US) 1982-02-23 US claimed
US-3991203-A Vehicle composition containing 1-substituted azacyclopentan-2-ones NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1976-11-09 US claimed
US-3989815-A PENETRATION OF SKINS NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1976-11-02 US claimed
US-3989816-A PENETRATION OF SKINS OR MEMBRANES NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1976-11-02 US claimed