Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 3/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2513062 | 0.94 | KMT2A (0.49) | KMT2AMEN1ALDH1A1MMP13STS | |
| SCHEMBL994328 | 0.94 | KMT2A (0.49) | KMT2AMEN1ALDH1A1MMP13STS | |
| SCHEMBL18137607 | 0.93 | KMT2A (0.54) | KMT2AMEN1ALDH1A1MMP13STS | |
| SCHEMBL18397145 | 0.91 | KMT2A (0.51) | KMT2AMEN1ALDH1A1MMP13STS | |
| SCHEMBL23348324 | 0.89 | STS (0.57) | ALDH1A1MMP13STS | |
| SCHEMBL21815402 | 0.83 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL22050819 | 0.82 | STS (0.62) | ALDH1A1MMP13STS | |
| SCHEMBL28527952 | 0.82 | KMT2A (0.50) | KMT2AMEN1ALDH1A1MMP13STS | |
| SCHEMBL25408371 | 0.82 | KMT2A (0.46) | KMT2AMEN1ALDH1A1MMP13STS | |
| SCHEMBL30397615 | 0.82 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1MMP13STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118750-A1 | IMIDAZO ISOINDOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118750-A1 | IMIDAZO ISOINDOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | IDO1, IDO2, TPH1 | KMT2A 1704/4885MEN1 498/4885ALDH1A1 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.