Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 6/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 2/20 | 0.34 |
| ▸ | ATP4B | P51164 | 2/20 | 0.34 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20100103 | 0.89 | KDM4E (0.51) | KDM4ELMNAHSD17B10CSNK1EATP4A | |
| SCHEMBL13542749 | 0.76 | HSD17B10 (0.54) | KDM4ELMNAHSD17B10CYP1A2SCN10A | |
| SCHEMBL3427346 | 0.76 | LMNA (0.54) | KDM4ELMNAHSD17B10CYP1A2SCN10A | |
| SCHEMBL12938095 | 0.74 | KDM4E (0.69) | KDM4ELMNAHSD17B10CYP1A2SCN10A | |
| SCHEMBL4107335 | 0.72 | HSD17B10 (0.61) | KDM4ELMNAHSD17B10CYP1A2SCN10A | |
| SCHEMBL22563409 | 0.70 | HSD17B10 (0.54) | KDM4ELMNAHSD17B10CYP1A2SCN10A | |
| SCHEMBL19911168 | 0.70 | HSD17B10 (0.62) | KDM4ELMNAHSD17B10CYP1A2SCN10A | |
| SCHEMBL12724845 | 0.70 | KDM4E (0.62) | KDM4ELMNAHSD17B10CYP1A2SCN10A | |
| SCHEMBL17300603 | 0.68 | HSD17B10 (0.61) | KDM4ELMNAHSD17B10CYP1A2SCN10A | |
| SCHEMBL8223435 | 0.68 | LMNA (0.61) | KDM4ELMNAHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180116222-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180116222-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, CBR3, CYCS | KDM4E 1838/4885LMNA 1472/4885HSD17B10 1027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.