Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CSNK1E | P49674 | 7/20 | 0.42 |
| ▸ | ATP4A | P20648 | 5/20 | 0.41 |
| ▸ | ATP4B | P51164 | 5/20 | 0.41 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.41 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.39 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.39 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.39 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20100076 | 0.89 | KDM4E (0.50) | KDM4ELMNAHSD17B10CSNK1EATP4A | |
| SCHEMBL8265318 | 0.79 | MAPT (0.46) | KDM4EHSD17B10CSNK1EATP4AATP4B | |
| SCHEMBL13542749 | 0.78 | HSD17B10 (0.54) | KDM4ELMNAHSD17B10 | |
| SCHEMBL3427346 | 0.78 | LMNA (0.54) | KDM4ELMNAHSD17B10NPY5R | |
| SCHEMBL8306086 | 0.76 | CSNK1E (0.42) | CSNK1EATP4AATP4BCSNK1G3ATP1A1 | |
| SCHEMBL15553070 | 0.76 | FABP6 (0.49) | CSNK1EATP4AATP4BCSNK1G3ATP1A1 | |
| SCHEMBL12938095 | 0.75 | KDM4E (0.69) | KDM4ELMNAHSD17B10 | |
| SCHEMBL12111156 | 0.75 | GAA (0.53) | CSNK1EATP4AATP4BCSNK1G3ATP1A1 | |
| SCHEMBL12109093 | 0.75 | CSNK1E (0.42) | KDM4ECSNK1EATP4AATP4BCSNK1G3 | |
| Bromide SCHEMBL16767404 | 0.74 | FABP6 (0.47) | CSNK1EATP4AATP4BCSNK1G3ATP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11072598-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2021-07-27 | — | — | US | disclosed |
| EP-3280716-B1 | IMIDAZO[1,2-A]PYRIDIN-2-YL DERIVATIVES AS PESTICIDES AND INTERMEDIATES THEREOF | BAYER CROPSCIENCE AG (DE) | 2020-02-12 | — | — | EP | disclosed |
| US-10188108-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-29 | — | — | US | disclosed |
| US-20180116222-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | US | disclosed |
| US-20180116222-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10188108-B2 | Fused bicyclic heterocycle derivatives as pesticides | DDT, CBR3, CYCS | KDM4E 1838/4885LMNA 1472/4885HSD17B10 1027/4885 |
| US-20180116222-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, CBR3, CYCS | KDM4E 1838/4885LMNA 1472/4885HSD17B10 1027/4885 |
| US-11072598-B2 | Somatostatin modulators and uses thereof | SSTR5, SSTR2, SSTR4 | KDM4E 4554/4885LMNA 3475/4885HSD17B10 3787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.