Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 2/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3743499 | 0.81 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL30194974 | 0.81 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL9309858 | 0.79 | ALDH1A1 (0.45) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL9312363 | 0.79 | ALDH1A1 (0.45) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL30003417 | 0.79 | KDM4E (0.74) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL14349080 | 0.79 | KDM4E (0.74) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL13894552 | 0.76 | ALDH1A1 (0.50) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL22788818 | 0.74 | KDM4E (0.67) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL13079413 | 0.74 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL14896293 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2868658-B1 | Method of preparation of stereospecific quinone derivatives | MEHTA DILIP (US) | 2018-05-02 | — | — | EP | disclosed |