Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30194974 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPK1SMN1; SMN2MCL1 | |
| SCHEMBL13894552 | 0.91 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPK1SMN1; SMN2MCL1 | |
| SCHEMBL7832858 | 0.87 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPK1SMN1; SMN2MCL1 | |
| SCHEMBL13894558 | 0.87 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPK1SMN1; SMN2MCL1 | |
| SCHEMBL3755837 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPK1SMN1; SMN2MCL1 | |
| SCHEMBL10488238 | 0.82 | ALDH1A1 (0.65) | ALDH1A1KDM4EMAPK1SMN1; SMN2MCL1 | |
| SCHEMBL13079413 | 0.81 | KDM4E (0.47) | ALDH1A1KDM4EMAPK1SMN1; SMN2MCL1 | |
| SCHEMBL20100147 | 0.81 | KDM4E (0.52) | ALDH1A1KDM4EMAPK1SMN1; SMN2MCL1 | |
| SCHEMBL3805142 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPK1SMN1; SMN2MCL1 | |
| SCHEMBL3743862 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPK1SMN1; SMN2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203161-B1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | UNIV INDIANA RES & TECH CORP (US) | 2018-05-09 | — | — | EP | disclosed |
| EP-2203161-B1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | UNIV INDIANA RES & TECH CORP (US) | 2018-05-09 | — | — | EP | disclosed |
| EP-2868658-B1 | Method of preparation of stereospecific quinone derivatives | MEHTA DILIP (US) | 2018-05-02 | — | — | EP | disclosed |
| US-9464021-B2 | Method of preparation of stereospecific quinone derivatives | MEHTA DILIP S (IN) | 2016-10-11 | — | — | US | disclosed |
| US-9464021-B2 | Method of preparation of stereospecific quinone derivatives | MEHTA DILIP S (IN) | 2016-10-11 | — | — | US | disclosed |
| US-9464021-B2 | Method of preparation of stereospecific quinone derivatives | MEHTA DILIP S (IN) | 2016-10-11 | — | — | US | disclosed |
| US-9089605-B2 | Quinone derivatives, pharmaceutical compositions, and uses thereof | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-07-28 | — | — | US | disclosed |
| US-9089605-B2 | Quinone derivatives, pharmaceutical compositions, and uses thereof | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-07-28 | — | — | US | disclosed |
| US-9089605-B2 | Quinone derivatives, pharmaceutical compositions, and uses thereof | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-07-28 | — | — | US | disclosed |
| US-20150126763-A1 | METHOD OF PREPARATION OF STEREOSPECIFIC QUINONE DERIVATIVES | MEHTA DILIP S (IN) | 2015-05-07 | — | — | US | disclosed |
| WO-2009042544-A1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2009-04-02 | — | — | WO | disclosed |
| EP-0737671-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5804601-A | USEFUL FOR TREATING ALZHEIMER'S DISEASE, MULTIPLE SCLEROSIS, BACTERIAL OR VIRAL MENINGITIS, DOWN'S SYNDROME AND PARKINSON'S DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-08 | — | — | US | disclosed |
| EP-0737671-A2 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-10-16 | — | — | EP | disclosed |
| US-5229385-A | Thromboxane A2 and lipoxygenase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-07-20 | — | — | US | disclosed |
| US-5106858-A | For disfunction of heart, brain, lung or kidney | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0234729-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4985447-A | USEFUL FOR TREATMENT AND PREVENTION OF DISEASES DUE TO DYSFUNCTION OF HEART, BRAIN, LUNG AND KIDNEY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4851413-A | TREATMENT OF HEART, BRAIN, LUNG OR KIDNEY DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0234729-A2 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126763-A1 | METHOD OF PREPARATION OF STEREOSPECIFIC QUINONE DERIVATIVES | UBE2D3, ULK3, UCK2 | ALDH1A1 706/4885KDM4E 3361/4885MAPK1 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.