SCHEMBL20100370

SCHEMBL20100370

C=C(C)C(=O)NC(C(=O)N(CC)C(=O)C(C)(C)C)C(F)F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20100399 0.87 TGFBR1 (0.34) TGFBR1
SCHEMBL20100378 0.72 TGFBR1 (0.36) TGFBR1
SCHEMBL20100345 0.65 TSHR (0.33)
SCHEMBL28461943 0.65 MEN1 (0.35)
SCHEMBL20100402 0.64
SCHEMBL14544847 0.63 CHRM2 (0.40)
SCHEMBL20100373 0.62 TGFBR1 (0.37) TGFBR1
SCHEMBL2766799 0.60 TGFBR1 (0.44) TGFBR1
Hydrochloric Acid SCHEMBL28335270 0.60 TGFBR1 (0.41) TGFBR1
SCHEMBL8948291 0.59 TGFBR1 (0.47) TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed