SCHEMBL20100399

SCHEMBL20100399

C=C(C)C(=O)NC(C(=O)N(CC)C(=O)C(C)(C)C)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.34
PLA2G2A P14555 1/20 0.30
PLA2G5 P39877 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20100370 0.87 TGFBR1 (0.33) TGFBR1
SCHEMBL20100373 0.72 TGFBR1 (0.37) TGFBR1
SCHEMBL20100345 0.71 TSHR (0.33)
SCHEMBL7999214 0.67 TGFBR1 (0.52) TGFBR1PLA2G2APLA2G5
SCHEMBL7999217 0.67 TGFBR1 (0.52) TGFBR1PLA2G2APLA2G5
SCHEMBL518302 0.66 TGFBR1 (0.40) TGFBR1PLA2G2APLA2G5
SCHEMBL4957746 0.66 TGFBR1 (0.40) TGFBR1PLA2G2APLA2G5
SCHEMBL3567097 0.66 CTSK (0.38) TGFBR1
SCHEMBL3567095 0.66 CTSK (0.38) TGFBR1
SCHEMBL28461943 0.66 MEN1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed