SCHEMBL20100378

SCHEMBL20100378

C=C(C)C(=O)NC(C(=O)N(C)C(=O)C(F)(F)F)C(F)F

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.36
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20100373 0.89 TGFBR1 (0.37) TGFBR1
SCHEMBL20100405 0.80 TGFBR1 (0.37) TGFBR1
SCHEMBL20100370 0.72 TGFBR1 (0.33) TGFBR1
SCHEMBL7999214 0.65 TGFBR1 (0.52) TGFBR1POLB
SCHEMBL7999217 0.65 TGFBR1 (0.52) TGFBR1POLB
SCHEMBL20457124 0.65 ALDH1A1 (0.31)
SCHEMBL20100352 0.64 TSHR (0.32)
SCHEMBL9004789 0.63 CHRM2 (0.38)
SCHEMBL1820299 0.61 TGFBR1 (0.50) TGFBR1TDP1
SCHEMBL2829465 0.61 TGFBR1 (0.43) TGFBR1POLBTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed