SCHEMBL20100423

SCHEMBL20100423

CCC(C)(C)C(=O)NC(=O)C1CCC(C(F)(F)F)CC1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.34
HSD11B1 P28845 1/20 0.34
CCR2 P41597 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PKM P14618 1/20 0.33
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33
PI4KB Q9UBF8 1/20 0.32
HSP90AB1 P08238 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
FKBP1A P62942 1/20 0.31
RIPK1 Q13546 3/20 0.31
LIPA P38571 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14997665 0.82 HSD17B10 (0.50) CCR2SMN1; SMN2HSD17B10ALDH1A1POLB
SCHEMBL15045365 0.80 HSD17B10 (0.49) HSD11B1CCR2SMN1; SMN2HSD17B10ALDH1A1
SCHEMBL14997667 0.80 HSD17B10 (0.49) HSD11B1CCR2SMN1; SMN2HSD17B10ALDH1A1
SCHEMBL15045364 0.80 HSD17B10 (0.49) HSD11B1CCR2SMN1; SMN2HSD17B10ALDH1A1
SCHEMBL17532392 0.78 PKM (0.43) CCR2ALDH1A1PKM
SCHEMBL28039756 0.72 CHRNB2 (0.38) GLASMN1; SMN2HSD17B10PTGDR2ALDH1A1
SCHEMBL20100334 0.71 PI4KB (0.33) GLASMN1; SMN2HSD17B10PTGDR2ALDH1A1
SCHEMBL4755628 0.70 NPSR1 (0.38) PTGDR2ALDH1A1POLBPI4KBRAB9A
SCHEMBL4755633 0.70 NPSR1 (0.38) PTGDR2ALDH1A1POLBPI4KBRAB9A
SCHEMBL12057466 0.69 POLB (0.48) GLASMN1; SMN2HSD17B10ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10042259-B2 Topcoat compositions and pattern-forming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-08-07 US disclosed
US-20180118970-A1 TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS ROHM AND HAAS ELECTRONIC MATERIALS LLC 2018-05-03 US disclosed