Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.30 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14428590 | 0.83 | RIPK1 (0.45) | RIPK1LMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL20100319 | 0.83 | RIPK1 (0.41) | RIPK1LMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL12017039 | 0.81 | RIPK1 (0.41) | RIPK1LMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL14838796 | 0.76 | RIPK1 (0.46) | RIPK1LMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL14997672 | 0.76 | RIPK1 (0.41) | RIPK1LMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL15045366 | 0.74 | RIPK1 (0.40) | RIPK1LMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL14997673 | 0.74 | RIPK1 (0.40) | RIPK1LMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL20100303 | 0.74 | RIPK1 (0.38) | RIPK1LMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL14612345 | 0.73 | RIPK1 (0.39) | RIPK1LMNAPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL13656146 | 0.73 | EPHX1 (0.39) | RIPK1LMNAPOLBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10042259-B2 | Topcoat compositions and pattern-forming methods | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2018-08-07 | — | — | US | disclosed |
| US-10042259-B2 | Topcoat compositions and pattern-forming methods | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2018-08-07 | — | — | US | disclosed |
| US-20180118970-A1 | TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS | ROHM AND HAAS ELECTRONIC MATERIALS LLC | 2018-05-03 | — | — | US | disclosed |
| US-20180118970-A1 | TOPCOAT COMPOSITIONS AND PATTERN-FORMING METHODS | ROHM AND HAAS ELECTRONIC MATERIALS LLC | 2018-05-03 | — | — | US | disclosed |