SCHEMBL20100524

SCHEMBL20100524

CN(C)c1ccc(C(C#N)(c2ccc(N(C)C)cc2)c2ccc(N(C)CCO)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.38
APP P05067 5/20 0.37
ALDH1A1 P00352 4/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TSHR P16473 2/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KDM4E B2RXH2 1/20 0.34
CCR1 P32246 1/20 0.34
NOX1 Q9Y5S8 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYBB P04839 1/20 0.33
NOX4 Q9NPH5 1/20 0.33
ADORA1 P30542 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14921136 0.82 ALDH1A1 (0.52) SLC2A1L3MBTL1APPALDH1A1MAPT
SCHEMBL7535570 0.82 SLC2A1 (0.54) SLC2A1APPALDH1A1MAPTMEN1
SCHEMBL14948220 0.77 APP (0.56) SLC2A1APPALDH1A1MAPTTSHR
SCHEMBL3834311 0.76 APP (0.48) SLC2A1APPALDH1A1MAPTMEN1
SCHEMBL3832743 0.76 APP (0.48) SLC2A1APPALDH1A1MAPTMEN1
SCHEMBL20100530 0.76 HTT (0.34) SLC2A1APPALDH1A1MAPTMEN1
SCHEMBL1800563 0.75 RELA (0.48) SLC2A1L3MBTL1ALDH1A1MAPTMEN1
SCHEMBL14112771 0.75 L3MBTL1 (0.44) SLC2A1L3MBTL1ALDH1A1TSHRHSD17B10
SCHEMBL13840830 0.74 MAPT (0.44) L3MBTL1APPALDH1A1MAPTMEN1
SCHEMBL5776081 0.74 L3MBTL1 (0.43) L3MBTL1APPALDH1A1KMT2ANOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200339815-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS MILLIKEN & COMPANY 2020-10-29 US disclosed
EP-3535371-B1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS PROCTER & GAMBLE (US) 2020-09-09 EP disclosed
US-10711139-B2 Leuco polymers as bluing agents in laundry care compositions MILLIKEN & COMPANY (US) 2020-07-14 US disclosed
US-20180119059-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 US disclosed
US-20180119059-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 US disclosed
US-20180118945-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS MILLIKEN & COMPANY 2018-05-03 US disclosed
US-20180118945-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS MILLIKEN & COMPANY 2018-05-03 US disclosed