SCHEMBL20100803

SCHEMBL20100803

CCC(C)(CC(C)(CC(C)(CC(C)(C)C(=O)Nc1ccc(O)cc1)C(=O)Nc1ccc(O)cc1)C(=O)Nc1ccc(O)cc1)C(=O)Nc1ccc(O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAPT P10636 7/20 0.43
L3MBTL1 Q9Y468 4/20 0.43
GAA P10253 4/20 0.43
THRB P10828 2/20 0.43
RECQL P46063 2/20 0.43
ALDH1A1 P00352 4/20 0.42
CYP1A1 P04798 2/20 0.42
CA12 O43570 1/20 0.42
BRD4 O60885 1/20 0.42
NR1I2 O75469 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
MB P02144 1/20 0.42
CA3 P07451 1/20 0.42
CYP3A4 P08684 1/20 0.42
RARG P13631 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26499184 1.00 MEN1 (0.46) MEN1KMT2ATDP1MAPTL3MBTL1
SCHEMBL26499202 0.87 PDK1 (0.46) MEN1KMT2ATDP1MAPTL3MBTL1
SCHEMBL97686 0.82 MEN1 (0.54) MEN1KMT2ATDP1MAPTL3MBTL1
SCHEMBL12890688 0.80 PDK1 (0.51) MEN1KMT2ATDP1MAPTL3MBTL1
SCHEMBL26499057 0.79 MEN1 (0.36) MEN1KMT2ATDP1MAPTL3MBTL1
SCHEMBL10110784 0.77 MEN1 (0.55) MEN1KMT2AMAPTL3MBTL1GAA
SCHEMBL12226380 0.75 L3MBTL1 (0.61) MEN1KMT2ATDP1MAPTL3MBTL1
SCHEMBL13992702 0.74 MAPT (0.35) MEN1KMT2ATDP1MAPTL3MBTL1
SCHEMBL18291139 0.73 MEN1 (0.48) MEN1KMT2ATDP1MAPTL3MBTL1
SCHEMBL26194900 0.73 POLB (0.55) MEN1KMT2ATDP1L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180120705-A1 PATTERN FORMING METHOD AND ELECTRONIC DEVICE MANUFACTURING METHOD FUJIFILM CORPORATION (JP) 2018-05-03 US disclosed