Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.78 |
| ▸ | COMT | P21964 | 6/20 | 0.69 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20100885 | 0.87 | FTO (1.00) | FTOCOMTEGFR | |
| SCHEMBL4970821 | 0.87 | FTO (0.76) | FTOCOMTEGFR | |
| SCHEMBL32669718 | 0.83 | FTO (0.71) | FTOCOMT | |
| SCHEMBL32669736 | 0.83 | FTO (0.81) | FTOCOMT | |
| SCHEMBL31520154 | 0.82 | FTO (0.70) | FTOCOMT | |
| SCHEMBL32669708 | 0.82 | FTO (0.66) | FTOCOMT | |
| SCHEMBL20100822 | 0.81 | COMT (1.00) | FTOCOMT | |
| SCHEMBL32669790 | 0.81 | FTO (0.69) | FTOCOMT | |
| SCHEMBL30740890 | 0.81 | FTO (0.69) | FTOCOMT | |
| SCHEMBL29493648 | 0.81 | COMT (1.00) | FTOCOMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922316-B | FTO inhibitors | 北京生命科学研究所 | 2022-04-08 | — | — | CN | disclosed |
| US-20180118665-A1 | FTO Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118665-A1 | FTO Inhibitors | FTO, ALKBH3, ALKBH1 | FTO 1/4885COMT 9/4885EGFR 4024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.