Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.58 |
| ▸ | PI4KA | P42356 | 3/20 | 0.58 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.58 |
| ▸ | SCN4A | P35499 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19253768 | 0.86 | PIK3CD (0.62) | PIK3CDPIK3CAPIK3CBPIK3CGPI4KA | |
| SCHEMBL20101123 | 0.79 | MEN1 (0.46) | PIK3CDPIK3CAPIK3CBPIK3CGPI4KA | |
| SCHEMBL25307122 | 0.74 | PI4KA (1.00) | PIK3CDPIK3CAPIK3CBPIK3CGPI4KA | |
| SCHEMBL31114551 | 0.74 | PI4KA (1.00) | PIK3CDPIK3CAPIK3CBPIK3CGPI4KA | |
| SCHEMBL1913811 | 0.74 | SCN4A (0.75) | PIK3CDPIK3CAPIK3CBPIK3CGPI4KA | |
| SCHEMBL30261092 | 0.74 | SCN4A (0.75) | PIK3CDPIK3CAPIK3CBPIK3CGPI4KA | |
| SCHEMBL30240959 | 0.73 | ALDH1A1 (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGPI4KA | |
| SCHEMBL19329204 | 0.73 | ALDH1A1 (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGPI4KA | |
| SCHEMBL25493442 | 0.72 | PI4KA (0.67) | PIK3CDPIK3CAPIK3CBPIK3CGPI4KA | |
| Hydrochloric Acid SCHEMBL9362913 | 0.72 | SCN4A (0.73) | PIK3CDPIK3CAPIK3CBPIK3CGPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081612-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | ACTAVALON, INC. (US) | 2018-05-03 | — | — | WO | disclosed |