Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 18/20 | 1.00 |
| ▸ | PI4KB | Q9UBF8 | 18/20 | 1.00 |
| ▸ | PIK3CA | P42336 | 17/20 | 1.00 |
| ▸ | PIK3CD | O00329 | 15/20 | 1.00 |
| ▸ | PIK3CB | P42338 | 14/20 | 1.00 |
| ▸ | PIK3CG | P48736 | 13/20 | 1.00 |
| ▸ | PIP5K1C | O60331 | 6/20 | 0.60 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.58 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | SCN4A | P35499 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31114551 | 1.00 | PI4KA (1.00) | PI4KAPI4KBPIK3CAPIK3CDPIK3CB | |
| SCHEMBL25304259 | 0.81 | PI4KA (0.69) | PI4KAPI4KBPIK3CAPIK3CDPIK3CB | |
| SCHEMBL31114760 | 0.81 | PI4KA (0.69) | PI4KAPI4KBPIK3CAPIK3CDPIK3CB | |
| SCHEMBL25493442 | 0.81 | PI4KA (0.67) | PI4KAPI4KBPIK3CAPIK3CDPIK3CB | |
| SCHEMBL29646253 | 0.80 | PIK3CA (0.82) | PI4KAPI4KBPIK3CAPIK3CDPIK3CB | |
| SCHEMBL5532470 | 0.80 | PIK3CA (0.82) | PI4KAPI4KBPIK3CAPIK3CDPIK3CB | |
| SCHEMBL17969171 | 0.80 | SCN4A (0.77) | PI4KAPI4KBPIK3CAPIK3CDPIK3CB | |
| SCHEMBL19253768 | 0.77 | PIK3CD (0.62) | PI4KAPI4KBPIK3CAPIK3CDPIK3CB | |
| SCHEMBL3708484 | 0.77 | SCN4A (0.62) | PI4KAPI4KBPIK3CAPIK3CDPIK3CB | |
| SCHEMBL31114667 | 0.76 | SCN4A (0.70) | PI4KAPI4KBPIK3CAPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382273-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INST NAT SANTE RECH MED (FR) | 2025-12-18 | — | — | US | disclosed |
| EP-4460500-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023131649-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023131649-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250382273-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | BBOX1, NDUFB6, NDUFB5 | PI4KA 4333/4885PI4KB 3022/4885PIK3CA 3378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.