Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20030887 | 0.86 | KCNH2 (0.45) | CNR1BRD4CREBBPCACNA1H | |
| SCHEMBL20030888 | 0.79 | CNR1 (0.43) | CNR1BRD4CREBBPMAPT | |
| SCHEMBL30987789 | 0.78 | CNR1 (0.46) | CNR1BRD4CREBBPCACNA1H | |
| SCHEMBL705027 | 0.78 | BRD4 (0.39) | CNR1BRD4CREBBPCACNA1HMAPK8 | |
| Trifluoroacetic Acid SCHEMBL31114899 | 0.76 | CNR1 (0.44) | CNR1BRD4CREBBPCACNA1HKDM4C | |
| SCHEMBL15345097 | 0.75 | BRD4 (0.44) | CNR1BRD4CREBBPCACNA1HKDM4E | |
| SCHEMBL29734603 | 0.74 | DDB1 (0.43) | CNR1KDM4C | |
| SCHEMBL22491582 | 0.74 | DDB1 (0.43) | CNR1KDM4C | |
| SCHEMBL30896811 | 0.74 | DDB1 (0.46) | CNR1BRD4CREBBPCACNA1HPDE7A | |
| SCHEMBL15333180 | 0.74 | BRD4 (0.43) | CNR1BRD4CREBBPCACNA1HMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118734-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118734-A1 | THERAPEUTIC COMPOUNDS | NQO1, HAVCR2, CCR5 | CNR1 1097/4885BRD4 1818/4885CREBBP 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.