SCHEMBL22491582

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29734603	1.00	DDB1 (0.43)	DDB1CRBNCYP1A2GRM4HTR1A
	SCHEMBL20030887	0.89	KCNH2 (0.45)	DDB1CRBNHTR1AHTR6MAPK1
	SCHEMBL8127288	0.83	DDB1 (0.43)	DDB1CRBNCYP1A2GRM4HTR1A
	SCHEMBL10737866	0.83	DDB1 (0.43)	DDB1CRBNCYP1A2GRM4SLC6A4
	SCHEMBL29688897	0.83	DDB1 (0.43)	DDB1CRBNCYP1A2GRM4HTR1A
	Hydrochloric Acid SCHEMBL10395915	0.82	DDB1 (0.43)	DDB1CRBNCYP1A2GRM4HTR1A
	Hydrochloric Acid SCHEMBL10396669	0.82	DDB1 (0.43)	DDB1CRBNCYP1A2GRM4SLC6A4
	SCHEMBL13201149	0.80	HTR2C (0.46)	DDB1CRBNCYP1A2GRM4MAPK1
	SCHEMBL31426763	0.80	DDB1 (0.52)	DDB1CRBNCYP1A2GRM4HTR6
	SCHEMBL27139046	0.80	DDB1 (0.52)	DDB1CRBNCYP1A2GRM4HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.