SCHEMBL705027

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15333180	0.94	BRD4 (0.43)	BRD4CREBBPMAPK8CNR1CACNA1H
	SCHEMBL17446850	0.88	HTT (0.41)	BRD4CREBBPMAPK8CNR1CACNA1H
	SCHEMBL681760	0.81	HTR4 (0.35)	MAPTMEN1KMT2AALDH1A1HTT
	SCHEMBL682829	0.81	GRM4 (0.37)	CNR1MAPTGRM4SIGMAR1MEN1
	SCHEMBL20030974	0.80	SIGMAR1 (0.34)	BRD4CREBBPMAPK8CNR1CACNA1H
	SCHEMBL18744649	0.79	CNR1 (0.35)	CNR1MAPTSIGMAR1MEN1KMT2A
	SCHEMBL20101161	0.78	CNR1 (0.44)	BRD4CREBBPMAPK8CNR1CACNA1H
	SCHEMBL15345097	0.76	BRD4 (0.44)	BRD4CREBBPCNR1CACNA1HCYP1A2
	SCHEMBL10737866	0.75	DDB1 (0.43)	BRD4CREBBPCYP1A2GRM4DDB1
	SCHEMBL682831	0.75	MAPT (0.34)	CNR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.