Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 3/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31602711 | 0.83 | GPR119 (0.45) | USP30DPP4MAP3K14GPR119RORC | |
| SCHEMBL18249669 | 0.82 | GPR119 (0.47) | USP30DPP4MAP3K14GPR119RORC | |
| SCHEMBL20164096 | 0.81 | GPR119 (0.45) | USP30DPP4MAP3K14GPR119CYP3A4 | |
| SCHEMBL24357345 | 0.80 | RORC (0.46) | USP30RORCFPR2PDE4BIDO1 | |
| SCHEMBL20164090 | 0.80 | DPP4 (0.45) | USP30DPP4MAP3K14GPR119RORC | |
| SCHEMBL31521322 | 0.79 | GPR119 (0.43) | USP30DPP4MAP3K14GPR119RORC | |
| SCHEMBL18249589 | 0.79 | GPR119 (0.47) | USP30DPP4MAP3K14GPR119RORC | |
| SCHEMBL18249625 | 0.79 | DPP4 (0.42) | USP30DPP4MAP3K14GPR119PDE4B | |
| SCHEMBL18249632 | 0.78 | DPP4 (0.47) | USP30DPP4MAP3K14GPR119RORC | |
| SCHEMBL31602843 | 0.77 | GPR119 (0.43) | USP30DPP4MAP3K14GPR119RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118734-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118734-A1 | THERAPEUTIC COMPOUNDS | NQO1, HAVCR2, CCR5 | USP30 4687/4885DPP4 1591/4885MAP3K14 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.