Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL399011 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HTTGAAALOX12HIF1A | |
| SCHEMBL28865246 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HTTGAAALOX12HIF1A | |
| SCHEMBL7442456 | 0.77 | ADRB2 (0.44) | ALDH1A1HTTGAAALOX12HIF1A | |
| SCHEMBL25898933 | 0.77 | PTGS1 (0.57) | ALDH1A1HTTGAAALOX12HIF1A | |
| SCHEMBL8676137 | 0.77 | LMNA (0.48) | ALDH1A1HTTGAAALOX12HIF1A | |
| SCHEMBL1406553 | 0.76 | ALDH1A1 (0.42) | ALDH1A1HTTGAAALOX12HIF1A | |
| SCHEMBL15449352 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HTTGAAALOX12HIF1A | |
| SCHEMBL9261774 | 0.75 | AKR1C3 (0.53) | HIF1ALMNASMN1; SMN2HPGDMAPT | |
| SCHEMBL741007 | 0.75 | ALDH1A1 (0.64) | ALDH1A1HTTGAAALOX12HIF1A | |
| SCHEMBL29549360 | 0.75 | ALDH1A1 (0.64) | ALDH1A1HTTGAAALOX12HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081672-A1 | BIARYL LIGANDS FOR TRANSITION METAL-CATALYZED REACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-03 | — | — | WO | disclosed |
| US-20180117574-A1 | BIARYL LIGANDS FOR TRANSITION METAL-CATALYZED REACTIONS | UNIV CALIFORNIA (US) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180117574-A1 | BIARYL LIGANDS FOR TRANSITION METAL-CATALYZED REACTIONS | EPHA2, L1CAM, ERBB2 | ALDH1A1 801/4885HTT 4829/4885GAA 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.