Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL408819 | 0.82 | NR4A2 (1.00) | NR4A2ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL13335079 | 0.80 | NR4A2 (0.50) | NR4A2ALDH1A1KDM4EL3MBTL1RORC | |
| SCHEMBL30309428 | 0.79 | NR4A2 (0.81) | NR4A2ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL28345593 | 0.79 | NR4A2 (0.81) | NR4A2ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL20108769 | 0.78 | SLC6A3 (0.53) | NR4A2ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL2441955 | 0.77 | SLC6A3 (0.65) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL8290173 | 0.74 | NR4A2 (0.69) | NR4A2ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL28878338 | 0.74 | NR4A2 (0.55) | NR4A2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL30114910 | 0.74 | HTT (0.71) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL7431522 | 0.74 | NR4A2 (0.56) | NR4A2ALDH1A1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180123057-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-05-03 | — | — | US | disclosed |
| US-20180123057-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180123057-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | BMI1, PIEZO1, ETV6 | NR4A2 2484/4885ALDH1A1 151/4885KDM4E 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.