SCHEMBL20102258

SCHEMBL20102258

CC1(C)c2ccccc2-c2ccc(N(c3ccc(-c4cccc5c4oc4ccc(-c6ccccc6)cc45)cc3)c3cc4ccccc4c4ccccc34)cc21

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.33
PTPRF P10586 1/20 0.31
PTPN2 P17706 1/20 0.31
PTPN1 P18031 1/20 0.31
PIM1 P11309 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9916331 0.93 ALOX5 (0.38) ALOX5
SCHEMBL9916629 0.93 ALOX5 (0.38) ALOX5
SCHEMBL20102252 0.93 ALOX5 (0.39) ALOX5
SCHEMBL20102241 0.93 PLA2G2A (0.32)
SCHEMBL25620821 0.92 ALOX5 (0.33) ALOX5PTPRFPTPN2PTPN1PIM1
SCHEMBL17126389 0.92 ALOX5 (0.40) ALOX5
SCHEMBL25620829 0.91 ALOX5 (0.33) ALOX5PTPRFPTPN2PTPN1PIM1
SCHEMBL17126400 0.91 ALOX5 (0.39) ALOX5
SCHEMBL25621867 0.91 ALOX5 (0.37) ALOX5PTPRFPTPN2PTPN1PIM1
SCHEMBL24586279 0.90 CA12 (0.33) PTPRFPTPN2PTPN1PIM1CSNK2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180123042-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-03 US disclosed
US-20180123042-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180123042-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME OR10J3, BMI1, ETV6 ALOX5 1874/4885PTPRF 920/4885PTPN2 637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.