SCHEMBL201023

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4567021	0.89	MRGPRX4 (0.45)	MRGPRX4RXRARXRBRXRGADAMTS4
	SCHEMBL2705638	0.84	LMNA (0.48)	LMNAHTTMRGPRX4RXRARXRB
	SCHEMBL202507	0.81	MRGPRX4 (0.53)	LMNAHTTMRGPRX4
	SCHEMBL202627	0.79	MAOB (0.56)	LMNAHTTMRGPRX4MEN1KMT2A
	SCHEMBL19285699	0.78	KDM1A (0.50)	LMNAHTTMRGPRX4PARP1
	SCHEMBL2707335	0.78	MRGPRX4 (0.54)	MRGPRX4RXRARXRBRXRGFFAR1
	SCHEMBL2705640	0.77	MRGPRX4 (0.52)	LMNAHTTMRGPRX4FFAR1
	SCHEMBL204212	0.77	PPARG (0.47)	LMNAHTTMRGPRX4PARP1MEN1
	SCHEMBL2705980	0.77	LMNA (0.49)	LMNAHTTMRGPRX4PARP1
	SCHEMBL201109	0.76	FFAR1 (0.51)	LMNAHTTMRGPRX4FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.