SCHEMBL20102390

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20102408	0.86	THRB (0.39)	THRBTHRAS1PR2S1PR1S1PR3
	SCHEMBL20111247	0.85	L3MBTL1 (0.35)	L3MBTL1THRBTHRAFGFR2TDP1
	SCHEMBL20102464	0.83	SMPD1 (0.41)	L3MBTL1MAPTALDH1A1RAB9AGAA
	SCHEMBL20102405	0.83	FGFR2 (0.34)	L3MBTL1THRBFGFR2TDP1MAPT
	SCHEMBL20102406	0.83	THRB (0.37)	L3MBTL1THRBTHRAS1PR1CHUK
	SCHEMBL15120821	0.83	L3MBTL1 (0.56)	L3MBTL1THRBTHRAS1PR2S1PR1
	SCHEMBL20102461	0.82	PPARG (0.32)	THRBTHRAHPGDALDH1A1PLA2G2D
	SCHEMBL20102417	0.82	THRB (0.38)	THRBTHRAS1PR2S1PR1S1PR3
	SCHEMBL20102409	0.81	ESR1 (0.38)	L3MBTL1THRBTHRACYP1A2CYP2C19
	SCHEMBL19160420	0.81	L3MBTL1 (0.55)	L3MBTL1THRBTHRAS1PR2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.